Chemical Name:L(-)-Epinephrine
CAS No.: 51-43-4
Molecular formula: C9H13NO3
Molecular weight: 183.2
Related categories:Pharmaceutical raw materials
Properties:
It is white or off-white crystalline powder, odorless and bitter. Very slightly soluble in water, insoluble in organic solvents such as ethanol and chloroform, soluble in mineral acid or sodium hydroxide solution. It is unstable in a neutral or alkaline aqueous solution, and the saturated aqueous solution is weakly alkaline. Commonly used in its hydrochloride, soluble in water, 0.1% aqueous solution pH is 2.5 ~ 5.0, this product and its salt in the case of oxides, alkalis, light and heat, are easily decomposed and metamorphosed into pink to brownish red.
Organogenesis
Adrenalin is secreted by the adrenal gland. The adrenal gland is a very important endocrine organ of the human body. It is called the adrenal gland because it is located above the kidneys on both sides. The adrenal gland is located one above the other, located above the kidney, and is jointly wrapped by the renal fascia and adipose tissue. The left adrenal gland is half-moon shaped and the right adrenal gland is triangular. The total weight of the adrenal glands is about 30 g. Viewed from the side, the glands are divided into two parts: the adrenal cortex and the adrenal medulla. The surrounding part is the cortex and the inner part is the medulla. The two are different in their occurrence, structure and function. They are actually two endocrine glands.
Chemical properties:
White crystalline powder. The temperature of 213 ° C (decomposition), soluble in mineral acid and alkali hydroxide solution, slightly soluble in water, insoluble in alcohol, ether, acetone, chloroform. Odorless, bitter. The air is exposed and the light is getting darker.
Overview:
Adrenaline, also known as accessory renin and para-renine, is extracted from the adrenal medulla of livestock (bovine, sheep) or artificially synthesized. It is a white or off-white crystalline powder and is excited by α and β receptors. effect. Adrenalin is a hormone secreted by chromaffin cells in the adrenal medulla. Mainly involved in the regulation of the sympathetic nervous system.
Nature:
Melting point | 215 °C (dec.)(lit.) |
Specific rotation | -51.5 o (c=4, 1M HCl, dry sub) |
Boiling point | 316.88°C (rough estimate) |
Density | 1.1967 (rough estimate) |
Refractive index | -51.5 ° (C=4, 1mol/L HCl) |
Storage conditions | 2-8°C |
Solubility | Practically insoluble in water, in ethanol (96 per cent) and in methylene chloride. It dissolves in hydrochloric acid. |
form | Fine Crystalline Powder |
Acidity coefficient (pKa) | 8.66(at 25℃) |
colour | White to light beige |
Water solubility | <0.01 g/100 mL at 18 oC |
Sensitivity | Air & Light Sensitive |
Merck | 14,3619 |
BRN | 2368277 |
stability | Stable. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents. Light sensitive. |
CAS database | 51-43-4(CAS DataBase Reference) |
NIST Chemical Information | L-adrenaline(51-43-4) |
EPA chemical information | 1,2-Benzenediol, 4-[(1R)-1-hydroxy-2-(methylamino) ethyl]-(51-43-4) |