Chemical Name:Dimethyl malonate
CAS No.: 108-59-8
Molecular formula: C5H8O4
Molecular weight: 132.11
Related categories: fatty acid methyl ester; pharmaceutical intermediates; general reagents; esters; Thiazoles; medicine; organic synthesis
Nature
Melting point | ?62 °C(lit.) |
Boiling point | 180-181 °C(lit.) |
Density | 1.156 g/mL at 25 °C(lit.) |
Vapor density | >1 (vs air) |
Refractive index | n20/D 1.413(lit.) |
Flash point | 194 °F |
Storage conditions | Store below +30°C. |
Solubility | alcohol: miscible |
form | Liquid |
colour | Clear colorless |
Explosive limit | 1.3-17.4%(V) |
Water solubility | negligible |
Merck | 14,6096 |
BRN | 774261 |
stability | Stable. Incompatible with strong oxidizing agents. Flammable. |
InChIKey | BEPAFCGSDWSTEL-UHFFFAOYSA-N |
CAS database | 108-59-8(CAS DataBase Reference) |
Chemical properties
Colorless liquid. Soluble in alcohol, ether and other organic solvents, slightly soluble in water.
Use
1. For pharmaceutical and organic synthesis
2. Dimethyl malonate is an important raw material for the production of pharmaceutical pipemidic acid. Foreign dimethyl malonate is mainly used as a raw material for producing pipemidic acid in a non-ethoxylated methylidene process, and reacts with orthoformate and urea to produce pipemidic acid. At present, most of the dimethyl malonate produced by related enterprises in China, except for the export, is mostly used to produce pipemidic acid.
3. Gas chromatographic analysis standards. Organic Synthesis.