Chemical Name:(R)-(-)-Epichlorohydrin
CAS No.: 51594-55-9
Molecular formula: C3H5ClO
Molecular weight: 92.52
Related Categories: Industrial/Fine Chemicals; Methyl Halides; chiral; CHIRAL COMPOUNDS; Chiral Compounds;
Nature
Melting point | -48°C |
Specific rotation | 34 o (589nm, c=1, MeOH) |
Boiling point | 114 °C(lit.) |
Density | 1.180 g/mL at 20 °C(lit.) |
Vapor density | 3.29 (vs air) |
Vapor Pressure | 10 mm Hg ( 16.6 °C) |
Refractive index | n20/D 1.438(lit.) |
Flash point | 33 °C |
Storage conditions | 2-8°C |
form | Liquid |
colour | Clear colorless to very pale yellow |
Explosive limit | 21% |
Water solubility | insoluble |
Merck | 14,3532 |
BRN | 1420785 |
CAS database | 51594-55-9(CAS DataBase Reference) |
Chemical properties
Boiling point 92-93 ° C (360 mm Hg).
Use
1. A variety of chiral pharmaceutical intermediates.
A chiral structural unit whose epoxy functional group can react with various nucleophiles to form chlorohydrin; for the synthesis of chiral morpholine and dioxane by Mitsunobu diol cyclization; as trans-2,4- Enantioselective Synthesis of Chiral Structural Units of Disubstituted Piperidines
2. For the synthesis of chiral intermediates and chiral drugs