Chemical Name:Doxazosin mesylate
CAS No.: 77883-43-3
Molecular formula: C24H29N5O8S
Molecular weight: 547.58
Related categories:Pharmaceutical raw materials; pharmaceutical intermediates; small molecule inhibitors
Appearance:
White or off-white crystalline powder Related substances: ≤1.0% dry weight loss: ≤1.0% ignition residue: ≤0.1% heavy metal: ≤10ppm content: ≥99.0%
Uses:
Primary mild-to-moderate hypertension, and hypertensive patients with benign prostatic hypertrophy. For patients who have difficulty controlling blood pressure with a single drug, doxazine can be combined with thiazide diuretics and beta-blockers, calcium antagonists or angiotensin converting enzyme inhibitors.
Melting point | 275-277°C |
Storage conditions | Desiccate at RT |
Solubility | Slightly soluble in water, soluble in a mixture of 15 volumes of water and 35 volumes of tetrahydrofuran, slightly soluble in methanol, practically insoluble in acetone. It shows polymorphism (5.9), some forms may be hygroscopic |
form | powder |
colour | white |
stability | Protect from light |
InChIKey | VJECBOKJABCYMF-UHFFFAOYSA-N |
CAS database | 77883-43-3(CAS DataBase Reference) |